Mercedes-Benz S-Class (2021 – 2025) Fuse Box Location & Diagrams
The Mercedes-Benz S-Class (2021–2025) combines luxury, innovation, and advanced electrical systems. Knowing the fuse box locations and fuse assignments helps diagnose electrical issues, replace blown fuses, and maintain vehicle functions efficiently. This guide provides clear fuse box locations, diagrams, and fuse details for quick reference.
Fuse Box Location
Passenger Compartment Fuse Box
Driver’s Side Fuse Box
Front Passenger Side Fuse Box
Engine Compartment Fuse Box
Luggage Compartment Fuse Box
Fuse Box Diagrams
Passenger Compartment Fuse Box
Driver’s Side Fuse Box
Mercedes-Benz S-Class (2021 – 2025)
Note: Fuses #231 and #232 are empty.
| № | Amps | Description |
|---|---|---|
| 200 | 10A | Diagnostic socket |
| 201 | 5A | COMAND |
| 202 | 5A | HV battery management system / Hybrid power electronics, Hybrid service disconnect |
| 203 | 7.5A | Telephone systems |
| 204 | 10A | Engine electronics |
| 205 | 7.5A | 360 degree view camera/reversing camera |
| 206 | 7.5A | Dynamic driving seat, Seat adjustment/seat climate control – front |
| 208 | 7.5A | DRIVE PILOT |
| 209 | 30A | Central control unit- front |
| 210 | 10A | 48V battery management system, HV battery management system / Hybrid power electronics, On-board battery charger plug-in |
| 211 | 30A | Door operating functions – front left (LL), Door operating functions – front right (RL), Front window lifters, Special equipment for special protection (Guard) |
| 212 | 30A | Luxury seat heating – front |
| 213 | 30A | Left belt tensioner – front (LL), Right belt tensioner- front (RL) |
| 214 | 30A | Door operating functions – rear left (RL), Power window- rear (RL) |
| 215 | 30A | Seat adjustment/seat climate control – front |
| 216 | 25A | Air suspension, E-ACTIVE BODY CONTROL |
| 218 | 15A | Steering wheel heating/steering wheel adjustment |
| 219 | 5A | Head-Up Display (Entry) |
| 7.5A | Head-Up Display (High) | |
| 220 | 7.5A | Perfume atomiser |
| 223 | 10A | COMAND |
| 224 | 10A | Instrument cluster |
| 225 | 7.5A | COMAND |
| 226 | 5A | A/C system / heater, Climate control control panel – front |
| 228 | 5A | COMAND |
| 229 | 5A | Telephone systems |
| 230 | 5A | ETC/Electronic Toll Collect |
Front Passenger Side Fuse Box
Mercedes-Benz S-Class (2021 – 2025)
| № | Amps | Description |
|---|---|---|
| 301 | 15A | Additional fuses for special-purpose vehicle, Special equipment for special protection (Guard) |
| 302 | 5A | Anti-theft alarm system |
| 303 | 5A | Auxiliary heating, COMAND, DRIVE PILOT, Emergency call system, Parking Assist, Telephone systems |
| 304 | 10A | Backup battery, Ignition lock, KEYLESS-GO |
| 305 | 5A | Anti-theft alarm system |
| 306 | Light/rain sensor | |
| 307 | A/C system / heater- rear, Climate control panel – rear | |
| 308 | HV battery management system / Hybrid power electronics, Starter motor 48V | |
| 309 | Tyre pressure monitor | |
| 310 | 48V battery management system | |
| 311 | Backup battery, Ignition lock | |
| 312 | CAR 2X COMMUNICATION | |
| 313 | Airbag systems | |
| 314 | A/C system / heater- rear, Climate control panel – rear | |
| 315 | Auxiliary heating | |
| 317 | AMG DYNAMIC SELECT | |
| 318 | 7.5A | Airbag systems |
| 319 | 7.5A | AMG Performance 4MATIC, Automatic transmission, Backup battery, Ignition lock, KEYLESS-GO |
| 320 | 10A | Reading lamps – rear, Roof lamps, Sun visor mirror lighting |
| 322 | 7.5A | Dynamic driving seat, Seat adjustment/seat climate control – front |
| 323 | 10A | DISTRONIC PLUS, Driving assistance system |
| 324 | 7.5A | Driving assistance system |
| 325 | 7.5A | Telephone systems |
| 326 | 30A | Door operating functions – front left (RL), Door operating functions – front right (LL), Front window lifters, Special equipment for special protection (Guard) |
| 327 | 30A | Seat adjustment/seat climate control – front |
| 328 | 30A | Door operating functions – rear left (LL), Power window- rear (LL) |
| 329 | 30A | Left belt tensioner- front (RL), Right belt tensioner- front (LL) |
| 330 | 7.5A | USB interface |
| 330 | 20A | USB Package Plus |
| 331 | 30A | COMAND |
| 332 | 30A | Luxury seat heating – front, |
| 333 | 30A | Panoramic glass roof (MAGIC SKY CONTROL) Sliding sunroof, Roller blind f. sliding sunroof/Panoramic glass roof, Special equipment for special protection (Guard) |
| 334 | 30A | Panoramic glass roof (MAGIC SKY CONTROL) Sliding sunroof, Roller blind f. sliding sunroof/Panoramic glass roof, Special equipment for special protection (Guard) |
| 335 | 30A | AMG DYNAMIC SELECT |
Engine Compartment Fuse Box
Mercedes-Benz S-Class (2021 – 2025)
| № | Amps | Description |
|---|---|---|
| 100 | 15A | Engine/transmission/HV battery cooling |
| 25A | Engine/transmission/HV battery cooling (AMG) | |
| 101 | 7.5A | Engine electronics (12-cyl. petrol), Engine electronics (4/6-cyl. petrol), Engine electronics (8-cyl. petrol) |
| 15A | Engine electronics (6-cyl. diesel) | |
| 102 | 20A | Engine electronics (12-cyl. petrol), Engine electronics (4/6-cyl. petrol) |
| 25A | Engine electronics (6-cyl. diesel), Engine electronics (8-cyl. petrol) | |
| 103 | 20A | Engine electronics (12-cyl. petrol), Engine electronics (8-cyl. petrol), Secondary air injection pump |
| 15A | Engine electronics (4/6-cyl. petrol), Engine electronics (6-cyl. diesel), Secondary air injection pump | |
| 103 | 25A | Engine electronics (48V 6-cyl. diesel), Secondary air injection pump |
| 104 | 20A | Engine electronics (12-cyl. petrol), Engine electronics (8-cyl. petrol) |
| 15A | Engine electronics (4/6-cyl. petrol), Engine electronics (6-cyl. diesel) | |
| 105 | 15A | Engine electronics (12-cyl. petrol), Engine electronics (4/6-cyl. petrol), Engine electronics (6-cyl. diesel) |
| 20A | Engine electronics (8-cyl. petrol) | |
| 107 | 25A | Lamps – front |
| 108 | 30A | Windscreen wipers |
| 109 | 7.5A | A/C system / heater, Inductive charging (high-voltage) |
| 110 | 10A | A/C system / heater |
| 111 | 30A | Central control unit- front |
| 112 | 30A | Windshield wiper recess heater |
| 113 | 25A | Lamps – front |
| 114 | 30A | Central control unit- front |
| 115 | 5A | ABS / ASR / ESP / BAS / Electrical parking brake, Gimbal reading lamp |
| 116 | 20A | Additional fuses for special-purpose vehicle |
| 117 | 30A | Starter motor 12 V |
| 40A | Starter motor 12 V (6 Cyl. Hybrid) | |
| 118 | 7.5A | Engine electronics, Engine/transmission/HV battery cooling, Haptic accelerator pedal module |
| 119 | 10A | Electrical exhaust flap, Engine electronics, HV battery management system / Hybrid power electronics |
| 120 | 10A | Engine electronics |
| 121 | 15A | Engine/transmission/HV battery cooling |
| 122 | 5A | Engine electronics |
| 123 | 10A | DRIVE PILOT (AMG) |
| 124 | 7.5A | Starter motor 12 V |
| 128 | 5A | ABS / ASR / ESP / BAS / Electrical parking brake |
| 129 | 5A | Central control unit- front |
| 136 | 40A | Secondary air injection pump |
| 139 | 5A | Engine electronics |
| 140 | 5A | 48V battery management system, AMG DYNAMIC SELECT, AMG Performance 4MATIC, Engine electronics |
| 141 | 7.5A | Engine electronics (48V) (6-cyl. diesel) |
| 142 | 10A | Automatic transmission, Voltage stabilising capacitor (Li-lon battery) |
| 143 | 20A | Engine/transmission/HV battery cooling (AMG) |
| 144 | 10A | DRIVE PILOT |
| 146 | 40A | ABS / ASR / ESP / BAS / Electrical parking brake |
| 30A | Engine/transmission/HV battery cooling (AMG) | |
| 147 | 5A | ABS / ASR / ESP / BAS / Electrical parking brake (Except AMG) |
| 30A | Engine/transmission/HV battery cooling (AMG) |
Luggage Compartment Fuse Box
Mercedes-Benz S-Class (2021 – 2025)
| № | Amps | Description |
|---|---|---|
| 401 | 7.5A | USB interface |
| 20A | USB Package Plus | |
| 402 | 15A | Refrigerator box |
| 403 | 15A | 12 V power socket, centre console, Cigar lighter, centre console |
| 404 | 15A | Engine Order Cancellation (EOC) / Road Noise Cancellation (RNC), Power socket in the boot |
| 405 | 15A | Cigar lighter – front |
| 407 | 5A | COMAND |
| 408 | 7.5A | Preparation Rear Seat Entertainment, Rear Seat Entertainment System |
| 409 | 5A | Telephone systems |
| 410 | 5A | Front contactless gesture control |
| 411 | 5A | Adaptive lighting in the rear |
| 412 | 10A | 115 V/230 V socket in the rear, Thermo cupholder |
| 413 | 20A | Auxiliary heating |
| 414 | 30A | Central control unit- rear, |
| 415 | 25A | Fuel system |
| 416 | 30A | Door operating functions – rear right, Power window- rear |
| 417 | 30A | Dynamic driving seat |
| 418 | 40A | BlueTEC, Rear axle steering (AMG) |
| 419 | 50A | Heated rear window |
| 420 | 40A | High-end sound system, Sound system |
| 421 | 30A | Central control unit- rear |
| 422 | 25A | 115 V/230 V socket in the rear |
| 423 | 30A | AMG: Engine Order Cancellation (EOC) / Road Noise Cancellation (RNC) |
| 424 | 30A | Individual luxury seats, seat heating – rear, Rear bench seat, seat heating |
| 425 | 20A | USB Package Plus |
| 426 | 30A | Remote boot lid closing/opening |
| 430 | 15A | HV battery management system / Hybrid power electronics |
| 431 | 7.5A | Communication module, Emergency call system |
| 432 | 7.5A | Driving assistance system |
| 433 | 10A | AMG DYNAMIC SELECT |
| 436 | 5A | Telephone sysctems |
| 437 | 7.5A | Ambient lighting |
| 438 | 7.5A | Parking Assist |
| 439 | 7.5A | Driving assistance system |
| 440 | 15A | A/C system / heater – rear |
| 441 | 5A | Remote boot lid closing/opening |
| 442 | 5A | BlueTEC |
| 445 | 7.5A | Telephone systems |
| 446 | 7.5A | Hybrid sound generator |
| 447 | 40A | High-end sound system |
| 450 | 30A | Rear seat belt extenders, Seat adjustment/seat climate control – rear |
| 451 | 30A | Rear seat belt extenders, Seat adjustment/seat climate control – rear |
| 452 | 30A | Individual luxury seats, seat heating – rear |
| 453 | 15A | On-board battery charger plug-in |
| 454 | 7.5A | Dynamic driving seat |
| 455 | 7.5A | Dynamic driving seat |
| 457 | 20A | AMG Performance 4MATIC |
| 458 | 30A | Front/rear heated armrest |
| 459 | 30A | Sound system subwoofer |
| 465 | 5A | Telephone systems |
| 466 | 15A | Rear Seat Entertainment System |
| 469 | 7.5A | DRIVE PILOT |
| 471 | 15A | Panic alarm system control unit / special signal system |
| 20A | Panic alarm system control unit / Trailer coupling | |
| 472 | 25A | Multifunction control unit for special-purpose vehicle |
| 473 | 25A | Multifunction control unit for special-purpose vehicle |
| 474 | 30A | Additional fuses for special-purpose vehicle, Trailer coupling |
| 475 | 20A | Trailer coupling |
| 475 | 30A | Special equipment for special protection (Guard) |
| 476 | 30A | Special equipment for special protection (Guard), Trailer coupling |
| 477 | 7.5A | Thermo cupholder |
| 478 | 15A | Panic alarm system control unit / special signal system |
| 30A | Panic alarm system control unit / Trailer coupling (30A) | |
| 481 | 25A | Convenience rear doors |
| 20A | Special equipment for special protection (Guard) | |
| 482 | 25A | Convenience rear doors |
| 20A | Special equipment for special protection (Guard) |
Additional fuse holder (Rear Compartment)
Mercedes-Benz S-Class (2021 – 2025)
| № | Amps | Description |
|---|---|---|
| 2 | 7.5A | DRIVE PILOT |
| 3 | 7.5A | DRIVE PILOT |
| 4 | 5A | DRIVE PILOT |
